ODCs

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1 OMIM reference -
1 associated gene
5 signs/symptoms

PROTEIN INTERACTIONS: 1

4 associated genes
No signs/symptoms info

Pyogenic bacterial infections due to MyD88 deficiency

Pediatric systemic lupus erythematosus


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	MYD88	(0.94)	IRAK1

Citations in the biomedical literature:

Pyogenic bacterial infections due to MyD88 deficiency		Pediatric systemic lupus erythematosus
	Synonym(s): - MyD88 deficiency		Synonym(s): - SLE, pediatric onset

	Classification (Orphanet): - Rare genetic disease - Rare immune disease		Classification (Orphanet): - Rare neurologic disease - Rare renal disease - Rare respiratory disease - Rare systemic or rheumatologic disease

	Classification (ICD10): - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -		Classification (ICD10): - Diseases of the musculoskeletal system and connective tissue -

	Epidemiological data: Class of prevalence: unknown Average age onset: childhood Average age of death: child / adolescent Type of inheritance: autosomal recessive		Epidemiological data: (no data available)

	External references: 1 OMIM reference - No MeSH references		External references: No OMIM references No MeSH references

Pyogenic bacterial infections due to MyD88 deficiency
	Very frequent - Autosomal recessive inheritance - Immunodeficiency / increased susceptibility to infections / recurrent infections Frequent - Chronic skin infection / ulcerations / ulcers / cancrum - Nasal congestion / sinusitis / rhinitis / rhinorrhea Occasional - Fever / chilling
Pediatric systemic lupus erythematosus
(no data available)